Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

Why do so many promising drugs fail? This article explores how spatial multiomics reveals hidden cell interactions, helping ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Researchers at the John Innes Center and the Earlham Institute are pioneering powerful single-cell visualization techniques that could unlock higher yields of global wheat. Firmly in their sights is ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

A whole developing wheat spike, 1mm scale. The blue represents fluorescent staining for DNA withing the nuclei. There are different coloured spots showing gene expression detected using the probes in ...