This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...
Why do so many promising drugs fail? This article explores how spatial multiomics reveals hidden cell interactions, helping ...
A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...
Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...
Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...
10d
Spatial map of bladder cancer reveals hidden tumor environments, new paths toward precision therapy
Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...
People communicate with each other, sometimes face to face, sometimes with a text message or phone call. Cells also communicate with each other, sometimes by touching and sometimes by sending signals ...
Over the past decade, the Human Cell Atlas community has accomplished something that will define a generation of biology.
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